Mentored presenters may have participated in these courses
Student Project Titles List
Mechanically Induced Endothelial Cell Inflammation
Elucidating the Role of Androgens in Calcific Aortic Valve Disease Progression in Porcine Aortic Valvular Interstitial Cells
Using Hydrogel Coatings to Alter Heart Valve Surfaces
Jane Grande-Allen’s research applies engineering analysis to understand and fight heart valve disease. This involves mechanical testing, biochemical measurements, and microstructural analysis of critical components found in the extracellular matrix (ECM) that makes up cardiac tissue. Her studies into the basic and applied physiology of heart valve tissue have shown that the ECM – collagen, elastin, glycosaminoglycans and proteoglycans – forms an intricate network of connective tissue that is influenced by valvular function, growth, and abnormalities.