Antonios Mikos headshot

WEBSITE(S)| https://chemistry.rice.edu/people/antonios-mikos

Mentored presenters may have participated in these courses

BIOE 400, BIOE 401, BIOC 310

Student Project Titles List

Incorporation of Ceramic and Pore Size Gradients into 3D Printed Scaffolds Containing Gelatin Methacrylate Fibers for Tissue Repair

Development of ceramic-based bioink to prepare gradient scaffolds for osteochondral regeneration

Factorial Study on Effects of Parameters of Gelatin Microparticle Synthesis on Size Distribution of Particles

Osteochondral Tissue Engineering Using 3D Printed Peptide-Patterned Scaffolds

Three-Dimensional Printing of Protein-Loaded Microparticles in a Poly(Propylene Fumarate) Scaffold

Click-Functionalized Hydrogels for Osteochondral Repair

Evaluating In Vitro Cytocompatibility of Encapsulated Mesenchymal Stem Cells in a Chondroitin Sulfate Crosslinked Poly(N-isopropylacrylamide)-Based Hydrogel

Development of a Mechanically Tunable 3D Microenvironment for Osteosarcoma Study

Research Areas

Current projects in the Mikos Research Group include: Investigating bone regeneration and repair using a biodegradable polymer scaffold, either by inducing post-implantation bone tissue growth or by seeding the scaffold with bone cells prior to implantation; Developing new rapid prototyping processing methods for manufacturing 3-D biodegradable polymer scaffolds of anatomical shapes with precise architecture; Fabricating injectable, in situ polymerizable, biodegradable composite scaffolds as carriers for bone and cartilage cells to improve the quality of tissue formed in localized areas after injury; Developing new flow perfusion bioreactors and examining the effects of mechanical forces and flow on three-dimensional cultures of bone cells and the production of extracellular matrix; Synthesizing new biomimetic materials that exhibit the mechanical responsiveness and biochemical processing capabilities of living cells and tissues; Investigating the controlled release of growth factors from polymeric scaffolds to induce regeneration cascades in bone and cartilage; Fabricating novel nanocomposites using nanoparticles and single-walled carbon nanotubes as reinforcing agents to improve mechanical properties of scaffolds for bone tissue engineering.